Estimation of hepatitis B virus cccDNA persistence in chronic infection using within-host evolutionary rates
Hepatitis B virus (HBV) infection is a major global health problem with over 240 million infected individuals at risk of developing progressive liver disease and hepatocellular carcinoma. HBV is an enveloped DNA virus that establishes its genome as an episomal, covalently closed circular DNA (cccDNA...
Main Authors: | , , , |
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Format: | Journal article |
Jezik: | English |
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Oxford University Press
2020
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