Estimation of hepatitis B virus cccDNA persistence in chronic infection using within-host evolutionary rates

Hepatitis B virus (HBV) infection is a major global health problem with over 240 million infected individuals at risk of developing progressive liver disease and hepatocellular carcinoma. HBV is an enveloped DNA virus that establishes its genome as an episomal, covalently closed circular DNA (cccDNA...

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Bibliografske podrobnosti
Main Authors: Lythgoe, KA, Lumley, SF, McKeating, JA, Matthews, PC
Format: Journal article
Jezik:English
Izdano: Oxford University Press 2020