Embryonic myosin is a regeneration marker to monitor utrophin-based therapies for DMD

Duchenne muscular dystrophy (DMD) is a lethal, X-linked muscle-wasting disease caused by lack of the cytoskeletal protein dystrophin. Constitutive utrophin expression, a structural and functional paralogue of dystrophin, can successfully prevent the dystrophic pathology in the dystrophin-deficient m...

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Bibliographic Details
Main Authors: Guiraud, S, Edwards, B, Squire, S, Moir, L, Berg, A, Babbs, A, Ramadan, N, Wood, M, Davies, K
Format: Journal article
Language:English
Published: Oxford University Press 2018