Investigating the role of the Abruptex region within the Notch receptor

<p>The aim of this project was to investigate the structure and function of the Abruptex (Ax) region within the Notch receptor. Previous data from <em>D. melanogaster</em> shows that missense mutations in this region (EGF24-29) lead to a phenotype indicative of increased signalling...

Full description

Bibliographic Details
Main Author: Rowntree, T
Other Authors: Handford, P
Format: Thesis
Language:English
Published: 2018