In vitro, in silico and in vivo studies of the structure and conformational dynamics of DNA Polymerase I

DNA polymerases are a family of molecular machines involved in high-fidelity DNA replication and repair, of which DNA polymerase I (Pol) is one the best-characterized members. Pol is a strand-displacing polymerase responsible for Okazaki fragment synthesis and base-excision repair in bacteria; it co...

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Détails bibliographiques
Auteur principal: Sustarsic, M
Autres auteurs: Kapanidis, A
Format: Thèse
Langue:English
Publié: 2015
Sujets: