Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population.

Age-related changes in DNA methylation have been implicated in cellular senescence and longevity, yet the causes and functional consequences of these variants remain unclear. To elucidate the role of age-related epigenetic changes in healthy ageing and potential longevity, we tested for association...

Full description

Bibliographic Details
Main Authors: Bell, J, Tsai, P, Yang, T, Pidsley, R, Nisbet, J, Glass, D, Mangino, M, Zhai, G, Zhang, F, Valdes, A, Shin, S, Dempster, E, Murray, R, Grundberg, E, Hedman, A, Nica, A, Small, K, Dermitzakis, E, McCarthy, M, Mill, J, Spector, T, Deloukas, P
Format: Journal article
Language:English
Published: 2012