Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations.

Children with Down's syndrome (DS) have an increased risk of developing acute lymphoblastic leukemia (ALL) and have a low frequency of established genetic aberrations. We aimed to determine which genetic abnormalities are involved in DS ALL. We studied the frequency and prognostic value of dele...

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Hlavní autoři:	Buitenkamp, T, Pieters, R, Gallimore, N, van der Veer, A, Meijerink, J, Beverloo, H, Zimmermann, M, de Haas, V, Richards, S, Vora, A, Mitchell, C, Russell, L, Schwab, C, Harrison, C, Moorman, A, van den Heuvel-Eibrink, MM, den Boer, M, Zwaan, C
Médium:	Journal article
Jazyk:	English
Vydáno:	2012

Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations Autor Buitenkamp, T, Pieters, R, Gallimore, N, van der Veer, A, Meijerink, J, Beverloo, H, Zimmermann, M, de Haas, V, Richards, S, Vora, A, Mitchell, C, Russell, L, Schwab, C, Harrison, C, Moorman, A, van den Heuvel-Eibrink, MM, den Boer, M, Zwaan, C

Vydáno 2012

Journal article

Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations.

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