Eculizumab in aquaporin-4-positive neuromyelitis optica spectrum disorder.

<p>BACKGROUND: Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing, autoimmune, inflammatory disorder that typically affects the optic nerves and spinal cord. At least two thirds of cases are associated with aquaporin-4 antibodies (AQP4-IgG) and complement-mediated damage to the cent...

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Main Authors: Pittock, S, Berthele, A, Fujihara, K, Kim, H, Levy, M, Palace, J, Nakashima, I, Terzi, M, Totolyan, N, Viswanathan, S, Wang, K, Pace, A, Fujita, K, Armstrong, R, Wingerchuk, D
Format: Journal article
Language:English
Published: Massachusetts Medical Society 2019