Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins

Inducing broad spectrum neutralizing antibodies against challenging pathogens such as HIV-1 is a major vaccine design goal, but may be hindered by conformational instability within viral envelope glycoproteins (Env). Chemical cross-linking is widely used for vaccine antigen stabilization, but how th...

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Bibliografiska uppgifter
Huvudupphovsmän:	Schiffner, T, Pallesen, J, Russell, RA, Dodd, J, de Val, N, LaBranche, CC, Montefiori, D, Tomaras, GD, Shen, X, Harris, SL, Moghaddam, AE, Kalyuzhniy, O, Sanders, RW, McCoy, LE, Moore, JP, Ward, AB, Sattentau, QJ
Materialtyp:	Journal article
Språk:	English
Publicerad:	Public Library of Science 2018

Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins

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