Are extensive T cell epitope polymorphisms in the Plasmodium falciparum circumsporozoite antigen, a leading sporozoite vaccine candidate, selected by immune pressure?

Geahča maid

• A survey of the Th2R and Th3R allelic variants in the circumsporozoite protein gene of P. falciparum parasites from western Thailand.
  Dahkki: Kumkhaek, C, et al.
  Almmustuhtton: (2004)
• The repeat region of the circumsporozoite protein is critical for sporozoite formation and maturation in Plasmodium
  Dahkki: Ferguson, D, et al.
  Almmustuhtton: (2014)
• Wild isolates of Plasmodium falciparum show extensive polymorphism in T cell epitopes of the circumsporozoite protein.
  Dahkki: Lockyer, M, et al.
  Almmustuhtton: (1989)
• Probing novel epitopes on the Plasmodium falciparum circumsporozoite protein for vaccine development
  Dahkki: Krenger, PS, et al.
  Almmustuhtton: (2024)
• Chimeric Plasmodium falciparum parasites expressing Plasmodium vivax circumsporozoite protein fail to produce salivary gland sporozoites
  Dahkki: Marin-Mogollon, C, et al.
  Almmustuhtton: (2018)