TCR beta spectratyping in RA: evidence of clonal expansions in peripheral blood lymphocytes.

OBJECTIVE: To compare the TCR beta repertoire of peripheral blood CD8 enriched (CD8+) and depleted (CD8-) T cells in rheumatoid arthritis (RA) patients and controls using CDR3 length analysis (spectratyping). METHODS: CD8+ and CD8- T cells were separated from 14 RA patients and 12 controls, using ma...

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Bibliographic Details
Main Authors: Hall, F, Thomson, K, Procter, J, Mcmichael, A, Wordsworth, B
Format: Journal article
Language:English
Published: 1998