Sixty years of placebo-controlled antipsychotic drug trials in acute schizophrenia: systematic review, Bayesian meta-analysis, and meta-regression of efficacy predictors

<strong>Objective:</strong> Antipsychotic drug efficacy may have decreased over the decades. We, therefore, present a comprehensive meta-analysis of all placebo-controlled trials in acute schizophrenia, we investigate which trial characteristics have changed over the years and which ones...

Full description

Bibliographic Details
Main Authors: Leucht, S, Leucht, C, Huhn, M, Chaimani, A, Mavridis, D, Helfer, B, Samara, M, Rabaioli, M, Bächer, S, Cipriani, A, Geddes, J, Salanti, G, Davis, J
Format: Journal article
Published: American Psychiatric Publishing 2017