Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice.
Using hepatitis B virus (HBV) transgenic mice as recipients of virus-specific cytotoxic T lymphocytes (CTLs), we recently showed that polymorphonuclear neutrophils (PMNs) and the matrix-degrading metalloproteinases (MMPs) they produce are necessary for the intrahepatic recruitment of antigen nonspec...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2007
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