Discontinuation of fucose therapy in LADII causes rapid loss of selectin ligands and rise of leukocyte counts.
Leukocyte adhesion deficiency type II (LADII) is a rare inherited disorder of fucose metabolism. Patients with LADII lack fucosylated glycoconjugates, including the carbohydrate ligands of the selectins, leading to an immunodeficiency caused by the lack of selectin-mediated leukocyte-endothelial int...
المؤلفون الرئيسيون: | Lühn, K, Marquardt, T, Harms, E, Vestweber, D |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2001
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مواد مشابهة
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Correction of leukocyte adhesion deficiency type II with oral fucose.
حسب: Marquardt, T, وآخرون
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Leukocyte adhesion deficiency II patients with a dual defect of the GDP-fucose transporter.
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Leukocyte adhesion deficiency II syndrome, a generalized defect in fucose metabolism.
حسب: Marquardt, T, وآخرون
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The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter.
حسب: Lühn, K, وآخرون
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The role of fucosylation in leukocyte adhesion deficiency II.
حسب: Vestweber, D, وآخرون
منشور في: (2004)