Discontinuation of fucose therapy in LADII causes rapid loss of selectin ligands and rise of leukocyte counts.

Leukocyte adhesion deficiency type II (LADII) is a rare inherited disorder of fucose metabolism. Patients with LADII lack fucosylated glycoconjugates, including the carbohydrate ligands of the selectins, leading to an immunodeficiency caused by the lack of selectin-mediated leukocyte-endothelial int...

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מידע ביבליוגרפי
Main Authors: Lühn, K, Marquardt, T, Harms, E, Vestweber, D
פורמט: Journal article
שפה:English
יצא לאור: 2001

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