Discontinuation of fucose therapy in LADII causes rapid loss of selectin ligands and rise of leukocyte counts.
Leukocyte adhesion deficiency type II (LADII) is a rare inherited disorder of fucose metabolism. Patients with LADII lack fucosylated glycoconjugates, including the carbohydrate ligands of the selectins, leading to an immunodeficiency caused by the lack of selectin-mediated leukocyte-endothelial int...
Үндсэн зохиолчид: | Lühn, K, Marquardt, T, Harms, E, Vestweber, D |
---|---|
Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
2001
|
Ижил төстэй зүйлс
-
Correction of leukocyte adhesion deficiency type II with oral fucose.
-н: Marquardt, T, зэрэг
Хэвлэсэн: (1999) -
Leukocyte adhesion deficiency II patients with a dual defect of the GDP-fucose transporter.
-н: Helmus, Y, зэрэг
Хэвлэсэн: (2006) -
Leukocyte adhesion deficiency II syndrome, a generalized defect in fucose metabolism.
-н: Marquardt, T, зэрэг
Хэвлэсэн: (1999) -
The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter.
-н: Lühn, K, зэрэг
Хэвлэсэн: (2001) -
The role of fucosylation in leukocyte adhesion deficiency II.
-н: Vestweber, D, зэрэг
Хэвлэсэн: (2004)