Assessment of repurposed compounds against coronaviruses highlights the antiviral broad-spectrum activity of host-targeting iminosugars and confirms the activity of potent directly acting antivirals

The COVID-19 pandemic highlights the need for novel antiviral drug discovery approaches that could dramatically shorten timelines from compound discovery to clinical development. At the beginning of the pandemic, repurposing approaches were at the forefront of early research efforts to screen for an...

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Main Authors: Brun, J, Arman, BY, Hill, ML, Kiappes, JL, Alonzi, DS, Makower, LL, Witt, KD, Gileadi, C, Rangel, V, Dwek, RA, Von Delft, A, Zitzmann, N
Format: Journal article
Jezik:English
Izdano: Elsevier 2025