Combining deep sequencing, proteomics, phosphoproteomics, and functional screens to discover novel regulators of sphingolipid homeostasis
Sphingolipids (SLs) are essential components of cell membranes and are broad-range bioactive signaling molecules. SL levels must be tightly regulated as imbalances affect cellular function and contribute to pathologies ranging from neurodegenerative and metabolic disorders to cancer and aging. Decip...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| פורמט: | Journal article |
| שפה: | English |
| יצא לאור: |
American Chemical Society
2016
|