A multiplex single nucleotide polymorphism typing assay for detecting mutations that result in decreased fluoroquinolone susceptibility in Salmonella enterica serovars Typhi and Paratyphi A.

OBJECTIVES: Decreased susceptibility to fluoroquinolones has become a major problem for the successful therapy of human infections caused by Salmonella enterica, especially the life-threatening typhoid and paratyphoid fevers. METHODS: By using Luminex xTAG beads, we developed a rapid, reliable and c...

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Bibliographic Details
Main Authors: Song, Y, Roumagnac, P, Weill, F, Wain, J, Dolecek, C, Mazzoni, C, Holt, K, Achtman, M
Format: Journal article
Language:English
Published: 2010