Functionalised pyrrolidinones by conjugate addition of stabilised enolates and reformatsky reagents
The α,β-unsaturated lactam 1b has been found to readily undergo conjugate addition reactions with a range of stabilised carbon nucleophiles and Reformatsky reagents under mild conditions in good yield with high diastereoselectivity. This method provides a simple and versatile approach to highly func...
| Hoofdauteurs: | , , |
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| Formaat: | Journal article |
| Taal: | English |
| Gepubliceerd in: |
1996
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| Samenvatting: | The α,β-unsaturated lactam 1b has been found to readily undergo conjugate addition reactions with a range of stabilised carbon nucleophiles and Reformatsky reagents under mild conditions in good yield with high diastereoselectivity. This method provides a simple and versatile approach to highly functionalised pyrrolidinones. |
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