Efficient pro-survival/angiogenic miRNA delivery by an MRI-detectable nanomaterial.

Herein, we report the use of biodegradable nanoparticles (NPs) containing perfluoro-1,5-crown ether (PFCE), a fluorine-based compound (NP170-PFCE) with the capacity to track cells in vivo by magnetic ressonance imaging (MRI) and efficiently release miRNA. NP170-PFCE complexed with miRNAs accumulate...

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Detalles Bibliográficos
Main Authors: Gomes, R, das Neves, R, Cochlin, L, Lima, A, Carvalho, R, Korpisalo, P, Dragneva, G, Turunen, M, Liimatainen, T, Clarke, K, Ylä-Herttuala, S, Carr, C, Ferreira, L
Formato: Journal article
Idioma:English
Publicado: 2013