Identification of major loci controlling clinical manifestations of ankylosing spondylitis.

Identification of major loci controlling clinical manifestations of ankylosing spondylitis.

OBJECTIVE: To identify genomic regions linked with determinants of age at symptom onset, disease activity, and functional impairment in ankylosing spondylitis (AS). METHODS: A whole genome linkage scan was performed in 188 affected sibling pair families with 454 affected individuals. Traits assesse...

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Bibliografische gegevens
Hoofdauteurs: Brown, M, Brophy, S, Bradbury, L, Hamersma, J, Timms, A, Laval, S, Cardon, L, Calin, A, Wordsworth, B
Formaat: Journal article
Taal:English
Gepubliceerd in: 2003

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