Identification of major loci controlling clinical manifestations of ankylosing spondylitis.

OBJECTIVE: To identify genomic regions linked with determinants of age at symptom onset, disease activity, and functional impairment in ankylosing spondylitis (AS). METHODS: A whole genome linkage scan was performed in 188 affected sibling pair families with 454 affected individuals. Traits assesse...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Brown, M, Brophy, S, Bradbury, L, Hamersma, J, Timms, A, Laval, S, Cardon, L, Calin, A, Wordsworth, B
Format: Journal article
Sprache:English
Veröffentlicht: 2003