Possible structural abnormality of the brainstem in unipolar depressive illness: a transcranial ultrasound and diffusion tensor magnetic resonance imaging study.

BACKGROUND: Most empirically derived antidepressants increase monoamine levels. The nuclei of cells synthesising these monoamines are located in the brainstem, and projection tracts such as the medial forebrain bundle reach virtually all other brain areas. Two studies of unipolar depressive illness...

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Bibliographic Details
Main Authors: Steele, J, Bastin, M, Wardlaw, J, Ebmeier, K
Format: Journal article
Language:English
Published: 2005