CAMPATH-1 antibodies in stem-cell transplantation.

BACKGROUND: CAMPATH-1 (CD52) Abs have been used in stem-cell transplants for the prevention of GvHD and graft rejection. These complications can effectively be prevented by depletion of T lymphocytes from both donor and recipient. However, donor lymphocytes might contribute an anti-leukemia effect...

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Bibliographic Details
Main Authors: Hale, G, Cobbold, S, Novitzky, N, Bunjes, D, Willemze, R, Prentice, H, Milligan, D, MacKinnon, S, Waldmann, H
Format: Journal article
Language:English
Published: 2001