Endocytosis of secretory granules in mouse pancreatic beta-cells evoked by transient elevation of cytosolic calcium.

Endocytosis of secretory granules in mouse pancreatic beta-cells evoked by transient elevation of cytosolic calcium.

1. To investigate the mechanisms regulating the reuptake of secretory granule membranes following regulated exocytosis, we have monitored changes in cell capacitance in single pancreatic beta-cells. 2. Membrane retrieval (endocytosis) occurred both in a continuous manner and in abrupt steps, corresp...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Eliasson, L, Proks, P, Ammälä, C, Ashcroft, F, Bokvist, K, Renström, E, Rorsman, P, Smith, P
التنسيق:	Journal article
اللغة:	English
منشور في:	1996

مواد مشابهة

Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells.
حسب: Bokvist, K, وآخرون
منشور في: (1995)

RELATIONSHIP BETWEEN EXOCYTOSIS AND ENDOCYTOSIS IN PANCREATIC B-CELLS
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CONTROL OF EXOCYTOSIS WITH B-CELL AT PROXIMAL AND DISTAL LEVELS OF THE SECRETORY CASCADE
حسب: Renstrom, E, وآخرون
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CORRELATION OF INTERNAL CALCIUM TRANSIENTS, EXOCYTOSIS AND THE RELEASE OF GRANULE CONTENTS IN PANCREATIC BETA-CELLS
حسب: Smith, P, وآخرون
منشور في: (1994)

Rapid ATP-dependent priming of secretory granules precedes Ca(2+)-induced exocytosis in mouse pancreatic B-cells.
حسب: Eliasson, L, وآخرون
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Stimulus-secretion coupling in pancreatic beta cells.
حسب: Ashcroft, F, وآخرون
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TOLBUTAMIDE STIMULATES EXOCYTOSIS BY DIRECT INTERACTION WITH THE SECRETORY MACHINERY IN B-CELLS
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DIRECT EVIDENCE FOR THE EXISTENCE OF HOT-SPOTS OF SECRETION IN MOUSE PANCREATIC BETA-CELLS
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منشور في: (1994)

Ca(2+)- and GTP-dependent exocytosis in mouse pancreatic beta-cells involves both common and distinct steps.
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منشور في: (1996)

A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells.
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CaM kinase II-dependent mobilization of secretory granules underlies acetylcholine-induced stimulation of exocytosis in mouse pancreatic B-cells.
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THE IMPORTANCE OF NA/CA-EXCHANGE IN RESTORING RESTING CYTOSOLIC CALCIUM LEVELS IN MOUSE BETA-CELLS
حسب: Bokvist, K, وآخرون
منشور في: (1995)

Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic B-cells.
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حسب: Ammälä, C, وآخرون
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Cooling inhibits exocytosis in single mouse pancreatic B-cells by suppression of granule mobilization.
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LOCAL INTRACELLULAR CA2+-GRADIENTS ASSOCIATED WITH CA2+ ENTRY INTO AND SECRETION FROM MOUSE PANCREATIC BETA-CELLS
حسب: Bokvist, K, وآخرون
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حسب: Ammälä, C, وآخرون
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Physical interaction between secretory granules and L-type calcium channels is required for fast exocytosis in B-cells
حسب: Renstrom, E, وآخرون
منشور في: (1998)

ATP-dependence of exocytosis in mouse pancreatic beta-cells
حسب: Eliasson, L, وآخرون
منشور في: (1997)

Effects of divalent cations on exocytosis and endocytosis from single mouse pancreatic beta-cells.
حسب: Proks, P, وآخرون
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SULFONYLUREA AND EXOCYTOSIS IN MOUSE BETA-CELLS - A POSSIBLE INTERACTION WITH PROTEIN-KINASE-C
حسب: Ammala, C, وآخرون
منشور في: (1994)

Cytoplasmic calcium transients due to single action potentials and voltage-clamp depolarizations in mouse pancreatic B-cells.
حسب: Rorsman, P, وآخرون
منشور في: (1992)

Alpha 2-adrenoreceptor stimulation does not inhibit L-type calcium channels in mouse pancreatic beta-cells.
حسب: Bokvist, K, وآخرون
منشور في: (1991)

Insulin granule dynamics in pancreatic beta cells.
حسب: Rorsman, P, وآخرون
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Diabetes - when insulin is trapped in the secretory granule?
حسب: Rorsman, P
منشور في: (2008)

Intracellular pH, cytosolic calcium concentration and electrical activity in RINm5F insulinoma cells.
حسب: Best, L, وآخرون
منشور في: (1994)

Separate processes mediate nucleotide-induced inhibition and stimulation of the ATP-regulated K(+)-channels in mouse pancreatic beta-cells.
حسب: Bokvist, K, وآخرون
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Phosphatidylinositol 4-kinase serves as a metabolic sensor and regulates priming of secretory granules in pancreatic beta cells.
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Ion channels, electrical activity and insulin secretion.
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Inhibition of ATP-regulated K(+)-channels by a photoactivatable ATP-analogue in mouse pancreatic beta-cells.
حسب: Ammälä, C, وآخرون
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EXOCYTOSIS IN MOUSE PANCREATIC B-CELLS IS REGULATED BY THE BALANCE BETWEEN PHOSPHORYLATION AND DEPHOSPHORYLATION
حسب: Rorsman, P, وآخرون
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Role for [Ca2+] microdomains in glucose-induced movement of GFP-tagged secretory granules.
حسب: Renstrom, E, وآخرون
منشور في: (1999)

Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.
حسب: Ammälä, C, وآخرون
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A NOVEL LOW-CONDUCTANCE K+-CHANNEL PRODUCING MEMBRANE-POTENTIAL OSCILLATIONS IN MOUSE PANCREATIC BETA-CELLS
حسب: Bokvist, K, وآخرون
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Demonstration of a novel apamin-insensitive calcium-activated K+ channel in mouse pancreatic B cells.
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Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization.
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Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta-cells.
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Cyclic AMP stimulates exocytosis in mouse B-cells by both PKA-dependent and PKA-independent mechanisms
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Dynamics of the cationic, bioelectrical and secretory responses to formycin A in pancreatic islet cells.
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Neurotransmitter-induced inhibition of exocytosis in insulin-secreting beta cells by activation of calcineurin.
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