Elevated apoptosis impairs epithelial cell turnover and shortens villi in TNF-driven intestinal inflammation
The intestinal epithelial monolayer, at the boundary between microbes and the host immune system, plays an important role in the development of inflammatory bowel disease (IBD), particularly as a target and producer of pro-inflammatory TNF. Chronic overexpression of TNF leads to IBD-like pathology o...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Springer Nature
2019
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