Validation of the type 1 insulin-like growth factor receptor as a therapeutic target in renal cancer

Purpose: Expression of the type 1 insulin-like growth factor receptor (IGF1R) confers adverse prognosis in clear cell renal cell cancer (CC-RCC). We recently showed that IGF1R expression is inhibited by the von Hippel-Lindau (VHL) tumor suppressor, and the IGF1R is up-regulated in CC-RCC, in which V...

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Những tác giả chính: Yuen, J, Akkaya, E, Wang, Y, Takiguchi, M, Peak, S, Sullivan, M, Protheroe, A, Macaulay, V
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2009