Genomic patterns of progression in smoldering multiple myeloma

We analyzed whole genomes of unique paired samples from smoldering multiple myeloma (SMM) patients progressing to multiple myeloma (MM). We report that the genomic landscape, including mutational profile and structural rearrangements at the smoldering stage is very similar to MM. Paired sample analy...

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Main Authors: Bolli, N, Maura, F, Minvielle, S, Gloznik, D, Szalat, R, Fullam, A, Martincorena, I, Dawson, K, Samur, M, Zamora, J, Tarpey, P, Davies, H, Fulciniti, M, Shammas, M, Tai, Y, Magrangeas, F, Moreau, P, Corradini, P, Anderson, K, Alexandrov, L, Wedge, D, Avet-Loiseau, H, Campbell, P, Munshi, N
格式: Journal article
出版: Nature Publishing Group 2018

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