Flow cytometric visualisation of cytokine production by CD3-CD56+ NK cells and CD3+CD56+ NK-T cells in whole blood.

BACKGROUND: Natural killer (NK) cells produce multiple cytokines with potential immune regulatory roles. We standardised a whole-blood flow cytometry method to visualise intracellular cytokine production by NK cells for the study of NK cell biology and for clinical monitoring. METHODS: With a three-...

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Bibliographic Details
Main Authors: Mendes, R, Bromelow, K, Westby, M, Galea-Lauri, J, Smith, I, O'Brien, M, Souberbielle, B
Format: Journal article
Language:English
Published: 2000