Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factors

Epigenetic modifications on chromatin play important roles in regulating gene expression. Although chromatin states are often governed by multilayered structure, how individual pathways contribute to gene expression remains poorly understood. For example, DNA methylation is known to regulate transcr...

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Bibliographic Details
Main Authors: Cusack, M, King, HW, Spingardi, P, Kessler, BM, Klose, RJ, Kriaucionis, S
Format: Journal article
Language:English
Published: Cold Spring Harbor Laboratory Press 2020