Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin.

Evidence suggests that nerve growth factor (NGF) is an important mediator in inflammatory pain states: NGF levels increase in inflamed tissue, and neutralization of endogenous NGF prevents the hyperalgesia which normally develops during inflammation of the skin. Here we asked whether NGF contributes...

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Bibliographic Details
Main Authors: Koltzenburg, M, Bennett, D, Shelton, D, McMahon, S
Format: Journal article
Language:English
Published: 1999