CD28-CD80 Interactions Control Regulatory T Cell Motility and Immunological Synapse Formation.
Regulatory T cells (Tregs) are essential for tolerance to self and environmental Ags, acting in part by downmodulating costimulatory molecules on the surface of dendritic cells (DCs) and altering naive CD4 T cell-DC interactions. In this study, we show that Tregs form stable conjugates with DCs befo...
المؤلفون الرئيسيون: | Thauland, T, Koguchi, Y, Dustin, M, Parker, D |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
American Association of Immunologists
2014
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مواد مشابهة
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The immunological synapse and CD28-CD80 interactions.
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CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse.
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Th1 and Th2 cells form morphologically distinct immunological synapses.
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F-actin driven CD28-CD80 localization in the Immune Synapse
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