Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the alpha-thalassemia myelodysplasia syndrome (ATMDS).

Inherited mutations of specific genes have elucidated the normal roles of the proteins they encode by relating specific mutations to particular phenotypes. But many potentially informative mutations in such genes are lethal early in development. Consequently, inherited mutations may not reflect all...

詳細記述

書誌詳細
主要な著者: Gibbons, R, Pellagatti, A, Garrick, D, Wood, W, Malik, N, Ayyub, H, Langford, C, Boultwood, J, Wainscoat, J, Higgs, D
フォーマット: Journal article
言語:English
出版事項: 2003