The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.
A polymorphism in the autophagy gene Atg16l1 is associated with susceptibility to inflammatory bowel disease (IBD); however, it remains unclear how autophagy contributes to intestinal immune homeostasis. Here, we demonstrate that autophagy is essential for maintenance of balanced CD4+ T cell respons...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
eLife Sciences Publications
2016
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