Cytotoxic T lymphocytes and viral evolution in primary HIV-1 infection.

Efforts to develop immune-based therapies for HIV infection have been impeded by incomplete definition of the immunological correlates of protection. Despite many precedents demonstrating that CD8(+) cytotoxic T lymphocytes are key mediators of protective anti-viral immunity in non-human animal mode...

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Bibliographic Details
Main Authors: Price, D, O'Callaghan, C, Whelan, J, Easterbrook, P, Phillips, R
Format: Conference item
Published: 1999