A model for all genomes: the role of transcription factories.

A model for all genomes involving one major architectural motif is presented: DNA or chromatin loops are tethered to "factories" through the transcription machinery-a polymerase (active or inactive) or its transcription factors (activators or repressors). These loops appear and disappear a...

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Bibliographic Details
Main Author: Cook, P
Format: Journal article
Language:English
Published: 2010