Implications of current therapeutic restrictions for primaquine and tafenoquine in the radical cure of vivax malaria

<p><b>Background:</b> </p><p>The 8-aminoquinoline antimalarials, the only drugs which prevent relapse of vivax and ovale malaria (radical cure), cause dose-dependent oxidant haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Patients wi...

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Bibliographic Details
Main Authors: Watson, J, Taylor, W, Bancone, G, Chu, C, Jittamala, P, White, N
Format: Journal article
Language:English
Published: Public Library of Science 2018