Hepatic miR-144 drives fumarase activity preventing NRF2 activation during obesity

<strong>Background and Aims</strong> Oxidative stress plays a key role in the development of metabolic complications associated with obesity, including insulin resistance and the most common chronic liver disease worldwide, nonalcoholic fatty liver disease. We have recently discovered th...

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Main Authors: Azzimato, V, Chen, P, Barreby, E, Morgantini, C, Levi, L, Vankova, A, Jager, J, Sulen, A, Diotallevi, M, Shen, JX, Miller, A, Ellis, E, Rydén, M, Näslund, E, Thorell, A, Lauschke, VM, Channon, KM, Crabtree, M, Haschemi, A, Craige, SM, Mori, M, Spallotta, F, Aouadi, M
Format: Journal article
Language:English
Published: Elsevier 2021