The Oncogene Metadherin Interacts with the Known Splicing Proteins YTHDC1, Sam68 and T-STAR and Plays a Novel Role in Alternative mRNA Splicing

Oncogenic metadherin is a key contributor to tumourigenesis with metadherin expression and cytoplasmic localisation previously linked to poor survival. A number of reports have shown metadherin localises specifically to nuclear speckles known to be rich in RNA-binding proteins including the splicing...

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Bibliographic Details
Main Authors: Luxton, H, Simpson, B, Mills, I, Brindle, N, Ahmed, Z, Stavrinides, V, Heavey, S, Stamm, S, Whitaker, H
Format: Journal article
Language:English
Published: MDPI 2019