Xenopus phospho-CDK7/cyclin H expressed in baculoviral-infected insect cells.
The cyclin-dependent kinase-activating kinase (CAK) catalyzes the phosphorylation of the cyclin-dependent protein kinases (CDKs) on a threonine residue (Thr160 in human CDK2). The reaction is an obligatory step in the activation of the CDKs. In higher eukaryotes, the CAK complex has been characteriz...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2001
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