The rise and fall of NMDA antagonists for ischemic stroke.

It has long been accepted that high concentrations of glutamate can destroy neurons, and this is the basis of the theory of excitotoxicity during brain injury such as stroke. Glutamate N-methyl-D-aspartate (NMDA) receptor antagonists such as Selfotel, Aptiganel, Gavestinel and others failed to show...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Hoyte, L, Barber, P, Buchan, A, Hill, MD
Format: Journal article
Sprache:English
Veröffentlicht: 2004