The genomic landscape of 2,023 colorectal cancers

Colorectal carcinoma (CRC) is a common cause of mortality1, but a comprehensive description of its genomic landscape is lacking2–9. Here we perform whole-genome sequencing of 2,023 CRC samples from participants in the UK 100,000 Genomes Project, thereby providing a highly detailed somatic mutational...

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Detalhes bibliográficos
Main Authors: Cornish, AJ, Gruber, AJ, Kinnersley, B, Chubb, D, Frangou, A, Caravagna, G, Noyvert, B, Lakatos, E, Wood, HM, Thorn, S, Culliford, R, Arnedo-Pac, C, Househam, J, Cross, W, Sud, A, Law, P, Leathlobhair, MN, Hawari, A, Woolley, C, Sherwood, K, Feeley, N, Gül, G, Fernandez-Tajes, J, Zapata, L, Church, DN, Tomlinson, IPM
Formato: Journal article
Idioma:English
Publicado em: Nature Research 2024