Emerging implications of policies on malaria treatment: genetic changes in the Pfmdr-1 gene affecting susceptibility to artemether–lumefantrine and artesunate–amodiaquine in Africa

Artemether-lumefantrine (AL) and artesunate-amodiaquine (AS-AQ) are the most commonly used artemisinin-based combination therapies (ACT) for treatment of Plasmodium falciparum in Africa. Both treatments remain efficacious, but single nucleotide polymorphisms (SNPs) in the Plasmodium falciparum multi...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Okell, L, Reiter, L, Ebbe, L, Baraka, V, Bisanzio, D, Watson, O, Bennett, A, Verity, R, Gething, P, Roper, C, Alifrangis, M
Fformat: Journal article
Iaith:English
Cyhoeddwyd: BMJ Publishing Group 2018