Dysregulation of neuronal Ca2+ linked channel linked to heightened sympathetic phenotype in prohypertensive states

Hypertension is associated with impaired nitric oxide (NO) - cyclic nucleotide (CN) - coupled intracellular calcium (Ca2+) homeostasis that enhances cardiac sympathetic neurotransmission. Because neuronal membrane CA2+ currents are reduced by NO-activated S-nitrosylation, we tested whether CNs affe...

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Bibliographic Details
Main Authors: Paterson, D, Larsen, H, Bardsley, E, Lefkimmiatis, K
Format: Journal article
Published: Society for Neuroscience 2016