Dysregulation of neuronal Ca2+ linked channel linked to heightened sympathetic phenotype in prohypertensive states
Hypertension is associated with impaired nitric oxide (NO) - cyclic nucleotide (CN) - coupled intracellular calcium (Ca2+) homeostasis that enhances cardiac sympathetic neurotransmission. Because neuronal membrane CA2+ currents are reduced by NO-activated S-nitrosylation, we tested whether CNs affe...
| Hauptverfasser: | , , , |
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| Format: | Journal article |
| Veröffentlicht: |
Society for Neuroscience
2016
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