Prostate-specific antigen (PSA) protein does not affect growth of prostate cancer cells in vitro or prostate cancer xenografts in vivo.

BACKGROUND: Prostate-specific antigen (PSA) is produced in high amounts by normal and malignant prostate cancer cells. PSA is a serine protease with substrates that include semenogelin I and II, insulin-like growth factor binding protein 3, fibronectin, and laminin. PSA, via its enzymatic activity,...

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Bibliographic Details
Main Authors: Denmeade, SR, Litvinov, I, Sokoll, L, Lilja, H, Isaacs, J
Format: Journal article
Language:English
Published: 2003