Prostate-specific antigen (PSA) protein does not affect growth of prostate cancer cells in vitro or prostate cancer xenografts in vivo.
BACKGROUND: Prostate-specific antigen (PSA) is produced in high amounts by normal and malignant prostate cancer cells. PSA is a serine protease with substrates that include semenogelin I and II, insulin-like growth factor binding protein 3, fibronectin, and laminin. PSA, via its enzymatic activity,...
Main Authors: | Denmeade, SR, Litvinov, I, Sokoll, L, Lilja, H, Isaacs, J |
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Format: | Journal article |
Language: | English |
Published: |
2003
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