Sitagliptin and Roux-en-Y gastric bypass modulate insulin secretion via regulation of intra-islet PYY

The gut hormone peptide tyrosine tyrosine (PYY) is critical for maintaining islet integrity and restoring islet function following Roux-en-Y gastric bypass (RYGB). The expression of PYY and its receptors (NPYRs) in islets has been documented but not fully characterized. Modulation of islet PYY by th...

Full description

Bibliographic Details
Main Authors: Guida, C, McCulloch, L, Godazgar, M, Stephen, S, Baker, C, Basco, D, Dong, J, Chen, D, Clark, A, Ramracheya, R
Format: Journal article
Language:English
Published: John Wiley & Sons Ltd 2017