Sitagliptin and Roux-en-Y gastric bypass modulate insulin secretion via regulation of intra-islet PYY

The gut hormone peptide tyrosine tyrosine (PYY) is critical for maintaining islet integrity and restoring islet function following Roux-en-Y gastric bypass (RYGB). The expression of PYY and its receptors (NPYRs) in islets has been documented but not fully characterized. Modulation of islet PYY by th...

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Detalhes bibliográficos
Main Authors: Guida, C, McCulloch, L, Godazgar, M, Stephen, S, Baker, C, Basco, D, Dong, J, Chen, D, Clark, A, Ramracheya, R
Formato: Journal article
Idioma:English
Publicado em: John Wiley & Sons Ltd 2017