Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.

Genome-wide association studies have discovered hundreds of loci associated with complex brain disorders, but it remains unclear in which cell types these loci are active. Here we integrate genome-wide association study results with single-cell transcriptomic data from the entire mouse nervous syste...

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Bibliographic Details
Main Authors: Bryois, J, Skene, NG, Hansen, TF, Kogelman, LJA, Watson, HJ, Liu, Z, Eating Disorders Working Group of the Psychiatric Genomics Consortium, International Headache Genetics Consortium, 23andMe Research Team, Brueggeman, L, Breen, G, Bulik, CM, Arenas, E, Hjerling-Leffler, J, Sullivan, PF
Other Authors: van Duijn, C
Format: Journal article
Language:English
Published: Nature Research 2020