Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice.

AIMS/HYPOTHESIS: Complex changes in gene expression are associated with insulin resistance and non-alcoholic fatty liver disease (NAFLD) promoted by feeding a high-fat diet (HFD). We used functional genomic technologies to document molecular mechanisms associated with diet-induced NAFLD. MATERIALS A...

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Bibliographic Details
Main Authors: Toye, A, Dumas, M, Blancher, C, Rothwell, A, Fearnside, J, Wilder, S, Bihoreau, M, Cloarec, O, Azzouzi, I, Young, S, Barton, R, Holmes, E, McCarthy, M, Tatoud, R, Nicholson, J, Scott, J, Gauguier, D
Format: Journal article
Language:English
Published: 2007