Genetic modification of primary human B cells to model high-grade lymphoma

Sequencing studies of diffuse large B cell lymphoma (DLBCL) have identified hundreds of recurrently altered genes. However, it remains largely unknown whether and how these mutations may contribute to lymphomagenesis, either individually or in combination. Existing strategies to address this problem...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Caeser, R, Di Re, M, Krupka, JA, Gao, J, Lara-Chica, M, Dias,JML, Cooke, SL, Fenner, R, Usheva, Z, Runge, HFP, Beer, PA, Eldaly, H, Pak, H-K, Park, C-S, Vassiliou, GS, Huntly, BJP, Mupo, A, Bashford-Rogers, RJM, Hodson, DJ
Format: Journal article
Język:English
Wydane: Nature Research 2019